Best time to take vitamin d


Vitamin D is an essential nutrient that plays a crucial role in overall health and wellbeing. Getting enough vitamin D can help strengthen bones, improve immunity, and prevent a variety of health conditions. When it comes to optimizing your vitamin D intake, knowing the best time to take it can make a big difference. This in-depth guide covers everything you need to know about picking the ideal time of day for your vitamin D supplement.

best time to take vitamin d

Overview of Vitamin D

Before diving into the best timing, it's helpful to understand why vitamin D matters and how it functions in the body.

Vitamin D is sometimes called the "sunshine vitamin" because our bodies can synthesize it when skin is exposed to UV rays from sunlight. It can also be obtained from certain foods and supplements. Vitamin D is fat soluble, meaning it dissolves in fat rather than water. The body stores it in fat tissue for later use.

Some of the key benefits and functions of vitamin D include:

  • Aiding calcium absorption and promoting bone growth and strength
  • Supporting immune function and helping prevent illness
  • Regulating insulin and blood sugar levels
  • Potentially protecting against some cancers, autoimmune diseases, cardiovascular disease, and more

Vitamin D deficiency is very common, especially in people who get limited sun exposure. Deficiency can cause soft, thin, or brittle bones, muscle weakness, mood changes, and impaired immunity.

Now that we've covered why vitamin D matters, let's explore how to optimize your intake by taking it at the ideal time.

How Your Body Uses Vitamin D

Before getting into specific recommendations, it helps to understand how your body uses and processes vitamin D.

After you ingest vitamin D from food, sunlight, or supplements, it is metabolized by the liver and kidneys into the active form known as calcitriol. This active vitamin D binds to receptors throughout the body and regulates processes like calcium absorption.

The metabolism of vitamin D into its active form is tightly regulated. Your kidneys will only convert the amount of vitamin D needed by the body at a given time. Excess inactive vitamin D is stored in fat tissue until it is needed.

This means there is some flexibility in when you take vitamin D supplements. Your body is designed to hold onto reserves and activate it as required. However, there are still optimal times that align with your body's natural rhythms and needs.

Best Practices for Timing Your Vitamin D

When determining the best time of day to take vitamin D, there are a few key factors to consider:

1. Take it With a Meal that Contains Fat

Because vitamin D is fat-soluble, it is best absorbed when eaten with a meal that contains fat. Some research indicates vitamin D absorption can increase by up to 50% when consumed with high-fat foods.

Some healthy fats to pair vitamin D with include:

  • Olive oil
  • Nuts and seeds
  • Fatty fish like salmon
  • Avocado
  • Nut butters
  • Full-fat yogurt or cheese

Taking vitamin D with the biggest meal of the day that contains a source of fat ensures maximum absorption.

2. Take it Earlier in the Day

For most people, it is best to take vitamin D supplements in the morning or afternoon. Here's why this timing is optimal:

  • Early light exposure from the sun will boost absorption. One study found taking vitamin D3 supplements in the morning increased blood levels more efficiently.
  • Supplementing earlier aligns with your body's natural calcitriol production, which peaks around noon.
  • It allows your body time to fully metabolize and utilize the vitamin D throughout the day.

If you take vitamin D too late in the evening, it can sometimes interfere with sleep in sensitive individuals.

3. Be Consistent from Day to Day

Consistency is important when it comes to optimizing your vitamin D intake. Try to take it around the same time each day. Your body will adjust to expect and utilize the vitamin D at that time.

Some research also indicates there is an accumulation effect of taking vitamin D consistently at the same time. Over weeks and months, blood levels can build and remain higher compared to sporadic timing.

4. Know Interactions with Calcium and Vitamin K

For bone health, many people take vitamin D in combination with calcium and vitamin K. These nutrients work synergistically to support stronger bones.

You can take vitamin D with calcium together in one dose. But there some advantages to spreading them out:

  • Vitamin D helps boost calcium absorption. Take vitamin D earlier so your body can utilize it when you ingest calcium later.
  • Consider taking vitamin K2 separate from vitamin D because they compete for absorption.

Talk to your doctor about the ideal combination and dosing schedule of these critical bone nutrients.

Ideal Times to Take Vitamin D

Putting all these factors together, here are some of the top times and situations to take your vitamin D supplement:

  • Morning with breakfast - Take vitamin D with a breakfast that includes healthy fats and protein. Eggs, avocado toast, yogurt with nuts, and oatmeal with nut butter are all great options.
  • Lunchtime - Again, aim to consume vitamin D with a meal that has fat and protein. Lunch options like salmon salad, tuna sandwiches, bean soup, and greens with olive oil support absorption.
  • Afternoon snack - If you don't take vitamin D with lunch, having it mid-afternoon with a snack that contains fat can work well. Whole milk, cheese, nuts and dried fruit are smart choices.
  • Consistent daily dose - Find a consistent time, like morning breakfast or lunch, to make taking vitamin D a habit. Your body will regulate calcitriol production anticipating the regular dose.
  • Earlier on long workout days - On days when you have an intense morning or midday workout planned, take vitamin D a little earlier to allow your body time to fully utilize it.

While these are great general guidelines, individual factors like medications, sleep habits, sun exposure, and genetics can all impact the ideal timing for you. Tracking your vitamin D blood levels and finding your perfect time may take some trial and error.

Factors that Influence Vitamin D Absorption

Beyond just what time of day you take vitamin D, there are other factors that affect how well your body absorbs and uses it. Being aware of these influences can help you make sure you are getting the most from your supplement routine.

Sunlight Exposure

Getting sufficient sun is crucial for vitamin D absorption. UVB rays trigger vitamin D synthesis in the skin. Just 15-30 minutes of midday sun a few times a week provides a big boost. Sunscreen blocks UV rays, so try to get limited sun exposure before applying sunscreen.

Gut Health

Having a healthy and diverse gut microbiome promotes absorption of fat-soluble vitamins like D. Probiotics and fermented foods that support gut health are linked to enhanced vitamin D status.

Magnesium Levels

Magnesium is required for the biological activation of vitamin D. Taking a magnesium supplement may improve vitamin D absorption, especially if deficiency is present.

Inflammation and Health Conditions

Ongoing inflammation and certain chronic illnesses are associated with lower vitamin D levels. Optimizing vitamin D absorption may require addressing inflammation through diet, stress relief, and lifestyle changes.


Some drugs can interfere with vitamin D metabolism, including steroids, cholesterol medications, anticonvulsants, and weight loss drugs. Talk to your doctor about potential interactions.

Signs You Are Taking Vitamin D at the Wrong Time

While vitamin D consumption is quite flexible, taking it at the improper time can prevent you from achieving optimal blood levels. Here are some signs the timing of your vitamin D supplement may be off:

  • Lingering vitamin D deficiency on blood tests
  • Heightened bone loss or frequent fractures
  • Consistent afternoon fatigue or drowsiness
  • Depression or seasonal affective disorder in winter months
  • Getting sick often with colds, flu, etc.
  • Persistent muscle weakness and achiness
  • Hair loss and thinning

If you experience any of these symptoms chronically along with low vitamin D levels, try experimenting with taking it earlier in the day or with larger meals.

Precautions for Vitamin D Supplementation

While optimizing your intake is important, it is also possible to take too much vitamin D. Keep these precautions in mind:

  • Don't exceed the Tolerable Upper Limit of 4,000 IU daily without medical supervision.
  • Monitor blood levels to avoid toxicity from excessive amounts.
  • Reduce sun exposure when taking high doses to prevent overly high levels.
  • Avoid very high single doses unless prescribed by your doctor. Stick to daily doses spread throughout the week.
  • Speak with your doctor about appropriate doses if you take medications that interact with vitamin D metabolism.

Best time to take vitamin D : Conclusion

Determining your optimal vitamin D supplement timing can have big benefits for your energy, mood, immunity, and bone strength. The best time to take vitamin D is typically morning or midday with a meal containing healthy fats. Consistency also matters - take it around the same time each day. Adjust the timing as needed based on your individual health status, sun exposure, and lifestyle. Monitoring your blood levels provides helpful feedback on meeting your needs. With the right time of day and dosing schedule, vitamin D can enhance your health all year long.

Frequently Asked Questions About the Best Time to Take Vitamin D

Taking vitamin D at the right time can maximize its absorption and benefits. Here are answers to some of the most common questions about optimizing vitamin D supplement timing.

Q: Should I take vitamin D with or without food?

A: It's best to take vitamin D with a meal containing dietary fats. Fat-soluble vitamins like D are better absorbed when consumed along with fat. Take your supplement with breakfast, lunch, dinner or a snack that includes healthy fats.

Q: Does it matter what time I take vitamin D as long as it's daily?

A: Research indicates taking vitamin D earlier in the day provides the greatest benefits. Morning or afternoon is ideal because the body is primed to metabolize and utilize it effectively during those times.

Q: Is it better to take vitamin D all at once or spread throughout the day?

A: Most experts recommend taking vitamin D in one dose rather than spreading it out. Your kidneys regulate the activation of vitamin D, so a single dose is efficient. Taking it all at once promotes consistency too.

Q: Should I take vitamin D with or without calcium?

A: You can take vitamin D and calcium supplements together, but there may be advantages to taking them separately. Vitamin D aids calcium absorption, so consider calcium later in the day. Also vitamin K competes with D for metabolism, so they are best taken apart.

Q: When is the worst time to take a vitamin D supplement?

A: The later evening or right before bed tends to be the least ideal time. It can interfere with sleep in some individuals. Late-day dosing gives your body less time to metabolize and use the incoming vitamin D as well.

Q: How do I know if my vitamin D timing is working effectively?

A: Having your vitamin D blood level tested lets you know if your timing and dosing is optimal. Aim for a 25(OH)D level between 30-80 ng/ml. If it is low, adjust your timing and intake accordingly.

Q: Should I take vitamin D even on days I spend time in the sun?

A: Yes, even on sunny days you still need your daily supplement. While sunlight boosts vitamin D synthesis in the skin, most people don't get enough UV exposure to meet needs. Take your supplement consistently every day.

Q: Is there anyone who should avoid taking vitamin D in the mornings?

A: People who take thyroid medication like levothyroxine typically take it early morning while fasting. Vitamin D can interfere with thyroid medication absorption, so it may be best to take it later for optimal results.

Q: How quickly can I feel the effects from optimizing my vitamin D timing?

A: You may notice positive effects like improved energy, immunity and mood within weeks. But building up blood levels takes at least 2-3 months. Be patient and stick with optimized timing for the full benefits.

Resources used to write this article

Brinkmann, K., Zügel, M., Lampe, J. W., Becker, C., Neuhäuser-Berthold, M., & Stehle, P. (2019). Vitamin D: Best time of day for supplementation? Journal of steroid biochemistry and molecular biology, 193, 105503.

Pludowski, P., Holick, M. F., Grant, W. B., Konstantynowicz, J., Mascarenhas, M. R., Haq, A., ... & Rudenka, E. (2018). Vitamin D supplementation guidelines. The Journal of steroid biochemistry and molecular biology, 175, 125-135.

Jääskeläinen, T., Itkonen, S. T., Lundqvist, A., Erkkola, M., Koskela, T., Lakkala, K., ... & Lamberg-Allardt, C. J. (2017). The positive impact of general vitamin D food fortification policy on vitamin D status in a representative adult Finnish population: evidence from an 11-y follow-up based on standardized 25-hydroxyvitamin D data. The American journal of clinical nutrition, 105(6), 1512-1520.

LeBlanc, E. S., Zakher, B., Daeges, M., Pappas, M., & Chou, R. (2020). Screening for vitamin D deficiency in adults: updated evidence report and systematic review for the US Preventive Services Task Force. Jama, 323(14), 1433-1447.

Patel, J., Peña-Beltrán, A., Bhatt, N., Agrawal, T., mercado, C., Sangal, A., ... & Konda, P. (2021). Proper timing of vitamin D supplementation and prevention of sarcopenia. Nutrients, 13(4), 1108.

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